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GENERAL
TITLE
CRYSTAL STRUCTURE OF TS-DHFR FROM CRYPTOSPORIDIUM HOMINIS IN COMPLEX WITH NADPH, FDUMP AND 2-(2-(4-((2-AMINO-4-OXO-4,7-DIHYDRO-3H- PYRROLO[2,3-D]PYRIMIDIN-5-YL)METHYL)BENZAMIDO)PHENYL)ACETIC ACID.
DATE LAST MODIFIED
18 Dec 2019
RELEASE
2 Oct 2019
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
2.89
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1016/J.EJMECH.2019.111673

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
CHUDEA4_4460 ESCHERICHIA COLI BL21(DE3) CRYPTOSPORIDIUM HOMINIS --
CHUDEA4_4460 ESCHERICHIA COLI BL21(DE3) CRYPTOSPORIDIUM HOMINIS --
CHUDEA4_4460 ESCHERICHIA COLI BL21(DE3) CRYPTOSPORIDIUM HOMINIS --
CHUDEA4_4460 ESCHERICHIA COLI BL21(DE3) CRYPTOSPORIDIUM HOMINIS --
CHUDEA4_4460 ESCHERICHIA COLI BL21(DE3) CRYPTOSPORIDIUM HOMINIS --
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402