6R8L

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 6R8L_A

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GENERAL

TITLE

HUMAN CYCLOPHILIN D IN COMPLEX WITH 1-((1S,9S,10S)-10-HYDROXY-12-OXA- 8-AZA-TRICYCLO[7.3.1.02,7]TRIDECA-2,4,6-TRIEN-4-YLMETHYL)-3- {2-[(R)- 2-(2-METHYLSULFANYL-PHENYL)-PYRROLIDIN-1-YL]-2-OXO-ETHYL}-UREA

DATE LAST MODIFIED

RELEASE

27 Nov 2019

OBSOLETE

CLASSIFICATION

ISOMERASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 43 21 2

RESOLUTION RANGE HIGH

1.64

RESOLUTION RANGE LOW

51.21

PUBMED ID

31635932

DOI

10.1016/J.BMCL.2019.126717

PDBe

6R8L

LIGANDS

2905448

Chains

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P30405	PPIF, CYP3	ESCHERICHIA COLI	HUMAN	PPIASE F,CYCLOPHILIN D,CYPD,CYCLOPHILIN F,MITOCHON ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402