6RSH

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 6RSH_1

Chain 6RSH_A

Chain 6RSH_B

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GENERAL

TITLE

STRUCTURE BASED OPTIMIZATION OF JAK1-ATP BINDING POCKET INHIBITORS IN THE AMINOPYRAZOLE CLASS

DATE LAST MODIFIED

RELEASE

8 Jul 2020

OBSOLETE

CLASSIFICATION

TRANSFERASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 21

RESOLUTION RANGE HIGH

1.71

RESOLUTION RANGE LOW

48.76

PUBMED ID

DOI

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P23458	JAK1, JAK1A, JAK1B	SPODOPTERA AFF. FRUGIPERDA 1 BOLD-2017	HUMAN	JANUS KINASE 1,JAK-1	Mutations
	P23458	JAK1, JAK1A, JAK1B	SPODOPTERA AFF. FRUGIPERDA 1 BOLD-2017	HUMAN	JANUS KINASE 1,JAK-1	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402