6T8X

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 6T8X_1

Chain 6T8X_A

Chain 6T8X_B

Chain 6T8X_C

Chain 6T8X_D

Chain 6T8X_E

Chain 6T8X_F

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GENERAL

TITLE

CRYSTAL STRUCTURE OF MAPKAPK2 (MK2) COMPLEXED WITH PF-3644022 AND 5- (4-BROMOPHENYL)-N-[4-(1-PIPERAZINYL)PHENYL]-N-(2-PYRIDINYLMETHYL)-2- FURANCARBOXAMIDE

DATE LAST MODIFIED

RELEASE

12 May 2021

OBSOLETE

CLASSIFICATION

IMMUNE SYSTEM

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

C 2 2 21

RESOLUTION RANGE HIGH

2.81

RESOLUTION RANGE LOW

143.67

PUBMED ID

DOI

PDBe

6T8X

LIGANDS

1825686 , 2733538 ,

Chains

Target Protein	Gene	Expression System	Organism	Synonims	Actions
P08151	MAPKAPK2	ESCHERICHIA COLI BL21(DE3)	HUMAN	MK2N-(2-PYRIDINYLMETHYL)-2-FURANCARBOXAMIDE
P02766	MAPKAPK2	ESCHERICHIA COLI BL21(DE3)	HUMAN	MK2N-(2-PYRIDINYLMETHYL)-2-FURANCARBOXAMIDE
Q99497	MAPKAPK2	ESCHERICHIA COLI BL21(DE3)	HUMAN	MK2N-(2-PYRIDINYLMETHYL)-2-FURANCARBOXAMIDE
Q99497	MAPKAPK2	ESCHERICHIA COLI BL21(DE3)	HUMAN	MK2N-(2-PYRIDINYLMETHYL)-2-FURANCARBOXAMIDE
P02766	MAPKAPK2	ESCHERICHIA COLI BL21(DE3)	HUMAN	MK2N-(2-PYRIDINYLMETHYL)-2-FURANCARBOXAMIDE
P49137	MAPKAPK2	ESCHERICHIA COLI BL21(DE3)	HUMAN	MK2N-(2-PYRIDINYLMETHYL)-2-FURANCARBOXAMIDE	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402