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6U2F

3D Structure View

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GENERAL
TITLE
PCSK9-FAB 7G7 COMPLEX BOUND TO CIS-1-AMINO-4-PHENYLCYCLOHEXANEACYL- WNLK(HR)IGLLR - NH2
DATE LAST MODIFIED
12 Aug 2020
RELEASE
5 Feb 2020
OBSOLETE
CLASSIFICATION
HYDROLASE/HYDROLASE INHIBITOR/IMMUNE SYS
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
I 2 2 2
RESOLUTION RANGE HIGH
2.94
RESOLUTION RANGE LOW
49.37
PUBMED ID
DOI
10.1021/ACSCHEMBIO.9B00899

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q8NBP7 PCSK9, NARC1, PSEC0052 CRICETULUS GRISEUS HUMAN NEURAL APOPTOSIS-REGULATED CONVERTASE 1, NARC-1, PROPROTEINCONVERTASE 9, PC9, SUBTILISIN/KEXIN-LIKE PROTEASE PC9, PCSK9 HUMAN
NEURAL APOPTOSIS-REGULATED CONVERTASE 1, NARC-1, P ...
Mutations
-- -- SYNTHETIC CONSTRUCT -- SYNTHETIC CONSTRUCT --
Q569X1 -- MUS MUSCULUS MOUSE -- MOUSE --
-- MUS MUSCULUS MOUSE -- MOUSE --
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402