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3D Structure View

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GENERAL
TITLE
BRAF-MEK COMPLEX WITH AMP-PCP BOUND TO BRAF
DATE LAST MODIFIED
26 Feb 2020
RELEASE
28 Aug 2019
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 31 2 1
RESOLUTION RANGE HIGH
2.886
RESOLUTION RANGE LOW
80.16
PUBMED ID
DOI
10.1038/S41594-019-0365-0
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q02750 MAP2K1, MEK1, PRKMK1 SPODOPTERA FRUGIPERDA HUMAN MKK1,ERK ACTIVATOR KINASE 1,MAPK/ERK KINASE 1,MEK 1 HUMAN
MKK1,ERK ACTIVATOR KINASE 1,MAPK/ERK KINASE 1,MEK ...
Mutations
P15056 BRAF, BRAF1, RAFB1 SPODOPTERA FRUGIPERDA HUMAN PROTO-ONCOGENE B-RAF,P94,V-RAF MURINE SARCOMA VIRAL ONCOGENEHOMOLOG B1 HUMAN
PROTO-ONCOGENE B-RAF,P94,V-RAF MURINE SARCOMA VIRA ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402