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GENERAL
TITLE
THE CRYSTAL STRUCTURE OF ANTI-APOPTOTIC MCL-1 PROTEIN IN COMPLEX WITH 2, 5-SUBSTITUTED BENZOIC ACID INHIBITOR 21
DATE LAST MODIFIED
25 Mar 2020
RELEASE
4 Mar 2020
OBSOLETE
CLASSIFICATION
APOPTOSIS/INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 61 2 2
RESOLUTION RANGE HIGH
2.9
RESOLUTION RANGE LOW
200
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.9B01442
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q07820 MCL1, BCL2L3 ESCHERICHIA COLI HUMAN BCL-2-LIKE PROTEIN 3,BCL2-L-3,BCL-2-RELATED PROTEINEAT/MCL1,MCL1/EAT HUMAN
BCL-2-LIKE PROTEIN 3,BCL2-L-3,BCL-2-RELATED PROTEI ...
Mutations
Q07820 MCL1, BCL2L3 ESCHERICHIA COLI HUMAN BCL-2-LIKE PROTEIN 3,BCL2-L-3,BCL-2-RELATED PROTEINEAT/MCL1,MCL1/EAT HUMAN
BCL-2-LIKE PROTEIN 3,BCL2-L-3,BCL-2-RELATED PROTEI ...
Mutations
Q07820 MCL1, BCL2L3 ESCHERICHIA COLI HUMAN BCL-2-LIKE PROTEIN 3,BCL2-L-3,BCL-2-RELATED PROTEINEAT/MCL1,MCL1/EAT HUMAN
BCL-2-LIKE PROTEIN 3,BCL2-L-3,BCL-2-RELATED PROTEI ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402