6U8B

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 6U8B_A

Chain 6U8B_B

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GENERAL

TITLE

DISCOVERY AND OPTIMIZATION OF SALICYCLIC ACID-DERIVED SULFONAMIDE INHIBITORS OF THE WDR5:MYC PROTEIN-PROTEIN INTERACTION

DATE LAST MODIFIED

8 Jan 2020

RELEASE

4 Dec 2019

OBSOLETE

CLASSIFICATION

TRANSCRIPTION

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1

RESOLUTION RANGE HIGH

1.26

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1021/ACS.JMEDCHEM.9B01411

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	I6X8D2	WDR5, BIG3	ESCHERICHIA COLI K-12	HUMAN	BMP2-INDUCED 3-KB GENE PROTEIN
	P78540	WDR5, BIG3	ESCHERICHIA COLI K-12	HUMAN	BMP2-INDUCED 3-KB GENE PROTEIN

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402