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GENERAL
TITLE
STRUCTURAL BASIS FOR THALIDOMIDE TERATOGENICITY REVEALED BY THE CEREBLON-DDB1-SALL4-POMALIDOMIDE COMPLEX
DATE LAST MODIFIED
22 Apr 2020
RELEASE
15 Apr 2020
OBSOLETE
CLASSIFICATION
LIGASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
3.58
RESOLUTION RANGE LOW
38.7
PUBMED ID
DOI
10.1038/S41594-020-0405-9
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q16531 DDB1, XAP1 SPODOPTERA FRUGIPERDA HUMAN
DDB P127 SUBUNIT,DNA DAMAGE-BINDING PROTEIN A,DDBA ...
Mutations
Q96SW2 CRBN, AD-006 SPODOPTERA FRUGIPERDA HUMAN -- Mutations
Q9UJQ4 SALL4, ZNF797 ESCHERICHIA COLI HUMAN
ZINC FINGER PROTEIN 797,ZINC FINGER PROTEIN SALL4
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402