6UVF

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 6UVF_1

Bioassembly 6UVF_2

Bioassembly 6UVF_3

Bioassembly 6UVF_4

Bioassembly 6UVF_5

Bioassembly 6UVF_6

Chain 6UVF_A

Chain 6UVF_B

Chain 6UVF_C

Chain 6UVF_D

Chain 6UVF_E

Chain 6UVF_F

Chain 6UVF_G

Chain 6UVF_H

Chain 6UVF_I

Chain 6UVF_J

Chain 6UVF_K

Chain 6UVF_L

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GENERAL

TITLE

CRYSTAL STRUCTURE OF BCL-XL BOUND TO COMPOUND 12: (R)-2-(3-([1,1'- BIPHENYL]-4-CARBONYL)-3-(4-METHYLBENZYL)UREIDO)-3- ((CYCLOHEXYLMETHYL)SULFONYL)PROPANOIC ACID

DATE LAST MODIFIED

26 May 2021

RELEASE

5 May 2021

OBSOLETE

CLASSIFICATION

APOPTOSIS/INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1 21 1

RESOLUTION RANGE HIGH

2.24

RESOLUTION RANGE LOW

47.52

PUBMED ID

33904752

DOI

10.1021/ACS.JMEDCHEM.0C01771

PDBe

LIGANDS

230 , , 2730972

Chains

Target Protein	Gene	Expression System	Organism	Synonims
P0A6T5	BCL2L1, BCL2L, BCLX	ESCHERICHIA COLI BL21(DE3)	HUMAN	BCL2-L-1,APOPTOSIS REGULATOR BCL-X
P0A6T5	BCL2L1, BCL2L, BCLX	ESCHERICHIA COLI BL21(DE3)	HUMAN	BCL2-L-1,APOPTOSIS REGULATOR BCL-X
P0A6T5	BCL2L1, BCL2L, BCLX	ESCHERICHIA COLI BL21(DE3)	HUMAN	BCL2-L-1,APOPTOSIS REGULATOR BCL-X
P0A6T5	BCL2L1, BCL2L, BCLX	ESCHERICHIA COLI BL21(DE3)	HUMAN	BCL2-L-1,APOPTOSIS REGULATOR BCL-X
P0A6T5	BCL2L1, BCL2L, BCLX	ESCHERICHIA COLI BL21(DE3)	HUMAN	BCL2-L-1,APOPTOSIS REGULATOR BCL-X
P0A6T5	BCL2L1, BCL2L, BCLX	ESCHERICHIA COLI BL21(DE3)	HUMAN	BCL2-L-1,APOPTOSIS REGULATOR BCL-X
P0A6T5	BCL2L1, BCL2L, BCLX	ESCHERICHIA COLI BL21(DE3)	HUMAN	BCL2-L-1,APOPTOSIS REGULATOR BCL-X
P0A6T5	BCL2L1, BCL2L, BCLX	ESCHERICHIA COLI BL21(DE3)	HUMAN	BCL2-L-1,APOPTOSIS REGULATOR BCL-X
P0A6T5	BCL2L1, BCL2L, BCLX	ESCHERICHIA COLI BL21(DE3)	HUMAN	BCL2-L-1,APOPTOSIS REGULATOR BCL-X
P0A6T5	BCL2L1, BCL2L, BCLX	ESCHERICHIA COLI BL21(DE3)	HUMAN	BCL2-L-1,APOPTOSIS REGULATOR BCL-X

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402