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6VPH

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GENERAL
TITLE
TPX2 RESIDUES 7-20 FUSED TO AURORA A RESIDUES 116-389 MODIFIED WITH CACODYLATE AND IN COMPLEX WITH AMP-PNP
DATE LAST MODIFIED
-
RELEASE
5 Aug 2020
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 61 2 2
RESOLUTION RANGE HIGH
2.14
RESOLUTION RANGE LOW
30
PUBMED ID
DOI
10.1126/SCISIGNAL.ABB6707
PDBe
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
O14965 -- ESCHERICHIA COLI HUMAN TARGETING PROTEIN FOR XKLP2,AURORA KINASE A,DIFFERENTIALLYEXPRESSED IN CANCEROUS AND NON-CANCEROUS LUNG CELLS 2,DIL-2,HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN 519,HEPATOCELLULARCARCINOMA-ASSOCIATED ANTIGEN 90,PROTEIN FLS353,RESTRICTED EXPRESSIONPROLIFERATION-ASSOCIATED PROTEIN 100,P100,AURORA 2,AURORA/IPL1-RELATED KINASE 1,HARK1,BREAST TUMOR-AMPLIFIED KINASE,SERINE/THREONINE-PROTEIN KINASE 15,SERINE/THREONINE-PROTEIN KINASE 6,SERINE/THREONINE-PROTEIN KINASE AURORA-A HUMAN
TARGETING PROTEIN FOR XKLP2,AURORA KINASE A,DIFFER ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402