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GENERAL
TITLE
CRYSTAL STRUCTURE OF BCL-XL IN COMPLEX WITH TETRAHYDROISOQUINOLINE- PYRIDINE BASED INHIBITORS
DATE LAST MODIFIED
4 Nov 2020
RELEASE
21 Oct 2020
OBSOLETE
CLASSIFICATION
APOPTOSIS/APOPTOSIS INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
1.6
RESOLUTION RANGE LOW
47.29
PUBMED ID
DOI
10.1021/ACSMEDCHEMLETT.9B00568
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q07817 BCL2L1, BCL2L, BCLX ESCHERICHIA COLI HUMAN
BCL2-L-1,APOPTOSIS REGULATOR BCL-X
Mutations
Q07817 BCL2L1, BCL2L, BCLX ESCHERICHIA COLI HUMAN
BCL2-L-1,APOPTOSIS REGULATOR BCL-X
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402