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GENERAL
TITLE
CRYSTAL STRUCTURE OF NSP15 ENDORIBONUCLEASE FROM SARS COV-2 IN THE COMPLEX WITH POTENTIAL REPURPOSING DRUG TIPIRACIL
DATE LAST MODIFIED
24 Feb 2021
RELEASE
20 May 2020
OBSOLETE
CLASSIFICATION
VIRAL PROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 63
RESOLUTION RANGE HIGH
1.85
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1038/S42003-021-01735-9
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P56689 REP, 1A-1B ESCHERICHIA COLI BL21(DE3) 2019-NCOV
NSP15 ENDORIBNUCLEASE
P0DTD1 REP, 1A-1B ESCHERICHIA COLI BL21(DE3) 2019-NCOV
NSP15 ENDORIBNUCLEASE
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402