6X4C

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 6X4C_1

Chain 6X4C_A

Chain 6X4C_B

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GENERAL

TITLE

CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH 7-(2- (2-(2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)ETHOXY)-4-FLUOROPHENOXY)- 5,8-DIMETHYL-2-NAPHTHONITRILE (JLJ658), A NON-NUCLEOSIDE INHIBITOR

DATE LAST MODIFIED

16 Dec 2020

RELEASE

22 Jul 2020

OBSOLETE

CLASSIFICATION

TRANSFERASE, HYDROLASE/NHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

C 1 2 1

RESOLUTION RANGE HIGH

2.85

RESOLUTION RANGE LOW

PUBMED ID

32643196

DOI

10.1002/PRO.3910

PDBe

6X4C

LIGANDS

547230

Chains

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P03366	GAG-POL	ESCHERICHIA COLI BL21(DE3)	HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 GROUP M	P66 RT	Mutations
	P03366	GAG-POL	ESCHERICHIA COLI BL21(DE3)	HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 GROUP M	--	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402