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GENERAL
TITLE
CRYSTAL STRUCTURE OF CANCER-ASSOCIATED G301D MUTANT OF U2AF65 BOUND TO ADML SPLICE SITE
DATE LAST MODIFIED
3 Feb 2021
RELEASE
7 Oct 2020
OBSOLETE
CLASSIFICATION
RNA BINDING PROTEIN/SPLICING
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
1.7
RESOLUTION RANGE LOW
38.71
PUBMED ID
DOI
10.1074/JBC.RA120.015339
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P26368 U2AF2, U2AF65 ESCHERICHIA COLI BL21 HUMAN U2 AUXILIARY FACTOR 65 KDA SUBUNIT,HU2AF65,U2 SNRNPAUXILIARY FACTOR LARGE SUBUNIT HUMAN
U2 AUXILIARY FACTOR 65 KDA SUBUNIT,HU2AF65,U2 SNRN ...
Mutations
-- -- SYNTHETIC CONSTRUCT -- SYNTHETIC CONSTRUCT --
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402