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GENERAL
TITLE
STRUCTURE OF HUMAN PREGNANE X RECEPTOR LIGAND BINDING DOMAIN BOUND TETHERED WITH SRC CO-ACTIVATOR PEPTIDE IN COMPLEX WITH (S,S)-1
DATE LAST MODIFIED
-
RELEASE
23 Sept 2020
OBSOLETE
CLASSIFICATION
NUCLEAR PROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.27
RESOLUTION RANGE LOW
44.94
PUBMED ID
DOI
10.1016/J.BMCL.2020.127531
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
O75469 NR1I2, PXR, NCOA1, BHLHE74, SRC1 ESCHERICHIA COLI BL21(DE3) HUMAN ORPHAN NUCLEAR RECEPTOR PAR1,ORPHAN NUCLEAR RECEPTOR PXR,PREGNANE X RECEPTOR,STEROID AND XENOBIOTIC RECEPTOR,SXR,NCOA-1,CLASSE BASIC HELIX-LOOP-HELIX PROTEIN 74,BHLHE74,PROTEIN HIN-2,RIP160,RENAL CARCINOMA ANTIGEN NY-REN-52,STEROID RECEPTOR COACTIVATOR 1,SRC-1 HUMAN
ORPHAN NUCLEAR RECEPTOR PAR1,ORPHAN NUCLEAR RECEPT ...
Mutations
O75469 NR1I2, PXR, NCOA1, BHLHE74, SRC1 ESCHERICHIA COLI BL21(DE3) HUMAN ORPHAN NUCLEAR RECEPTOR PAR1,ORPHAN NUCLEAR RECEPTOR PXR,PREGNANE X RECEPTOR,STEROID AND XENOBIOTIC RECEPTOR,SXR,NCOA-1,CLASSE BASIC HELIX-LOOP-HELIX PROTEIN 74,BHLHE74,PROTEIN HIN-2,RIP160,RENAL CARCINOMA ANTIGEN NY-REN-52,STEROID RECEPTOR COACTIVATOR 1,SRC-1 HUMAN
ORPHAN NUCLEAR RECEPTOR PAR1,ORPHAN NUCLEAR RECEPT ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402