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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE KDR (VEGFR2) KINASE DOMAIN IN COMPLEX WITH A TYPE-II INHIBITOR BEARING AN ACRYLAMIDE
DATE LAST MODIFIED
17 Jun 2020
RELEASE
27 May 2020
OBSOLETE
CLASSIFICATION
SIGNALING PROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
1.98
RESOLUTION RANGE LOW
48.52
PUBMED ID
DOI
10.1021/JACS.9B13391
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P35968 KDR, FLK1, VEGFR2 SPODOPTERA FRUGIPERDA HUMAN VEGFR-2,FETAL LIVER KINASE 1,FLK-1,KINASE INSERT DOMAINRECEPTOR,KDR,PROTEIN-TYROSINE KINASE RECEPTOR FLK-1 HUMAN
VEGFR-2,FETAL LIVER KINASE 1,FLK-1,KINASE INSERT D ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402