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GENERAL
TITLE
STRUCTURE OF ALDOSTERONE SYNTHASE (CYP11B2) IN COMPLEX WITH 5-CHLORO- 3,3-DIMETHYL-2-[5-[1-(1-METHYLPYRAZOLE-4-CARBONYL)AZETIDIN-3-YL]OXY- 3-PYRIDYL]ISOINDOLIN-1-ONE
DATE LAST MODIFIED
22 Jul 2020
RELEASE
24 Jun 2020
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
I 2 2 2
RESOLUTION RANGE HIGH
2.77
RESOLUTION RANGE LOW
48.58
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.0C00233
PDBe
6XZ9
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| P21579 | CYP11B2 | ESCHERICHIA COLI | HUMAN | ALDOSTERONE SYNTHASE,ALDOS,ALDOSTERONE-SYNTHESIZIN ... | ||
| P60881 | CYP11B2 | ESCHERICHIA COLI | HUMAN | ALDOSTERONE SYNTHASE,ALDOS,ALDOSTERONE-SYNTHESIZIN ... | ||
| P63045 | CYP11B2 | ESCHERICHIA COLI | HUMAN | ALDOSTERONE SYNTHASE,ALDOS,ALDOSTERONE-SYNTHESIZIN ... |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402