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GENERAL
TITLE
CRYSTAL STRUCTURE OF MKK7 (MAP2K7) IN COMPLEX WITH IBRUTNIB, WITH COVALENT AND ALLOSTERIC BINDING MODES
DATE LAST MODIFIED
28 Oct 2020
RELEASE
12 Aug 2020
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2
RESOLUTION RANGE LOW
19.55
PUBMED ID
DOI
10.1016/J.CHEMBIOL.2020.07.014
PDBe
6YG2
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| P01867 | MAP2K7, JNKK2, MEK7, MKK7, PRKMK7, SKK4 | ESCHERICHIA COLI BL21(DE3) | HUMAN | MAPKK 7,JNK-ACTIVATING KINASE 2,MAPK/ERK KINASE 7, ... |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402