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GENERAL
TITLE
CRYO-EM STRUCTURE OF THE HUMAN TOPOISOMERASE II ALPHA DNA- BINDING/CLEAVAGE DOMAIN IN STATE 2
DATE LAST MODIFIED
2 Jun 2021
RELEASE
26 May 2021
OBSOLETE
CLASSIFICATION
ISOMERASE
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
4.1
RESOLUTION RANGE LOW
4.1
PUBMED ID
DOI
10.1038/S41467-021-23136-6
PDBe
--
LIGANDS
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| P11388 | TOP2A, TOP2 | VACCINIA VIRUS ANKARA | HUMAN | DNA TOPOISOMERASE II,ALPHA ISOZYME | Mutations | |
| P11388 | TOP2A, TOP2 | VACCINIA VIRUS ANKARA | HUMAN | DNA TOPOISOMERASE II,ALPHA ISOZYME | Mutations | |
| Q8C0L6 | -- | -- | HUMAN | -- | ||
| -- | -- | HUMAN | -- | |||
| -- | -- | HUMAN | -- | |||
| -- | -- | HUMAN | -- |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402