3D Structure View
Loading...
More Info
GENERAL
TITLE
STRUCTURAL BASIS OF REACTIVATION OF ONCOGENIC P53 MUTANTS BY A SMALL MOLECULE: METHYLENE QUINUCLIDINONE (MQ). HUMAN P53DBD-R273H MUTANT BOUND TO DNA: R273H-DNA
DATE LAST MODIFIED
15 Dec 2021
RELEASE
8 Dec 2021
OBSOLETE
CLASSIFICATION
TRANSCRIPTION
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
1.9
RESOLUTION RANGE LOW
45
PUBMED ID
DOI
10.1038/S41467-021-27142-6
PDBe
7B4A
LIGANDS
,
23
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| P28720 | TP53, P53 | ESCHERICHIA COLI BL21(DE3) | HUMAN | ANTIGEN NY-CO-13,PHOSPHOPROTEIN P53,TUMOR SUPPRESS ... | ||
| Q9WZM6 | TP53, P53 | ESCHERICHIA COLI BL21(DE3) | HUMAN | ANTIGEN NY-CO-13,PHOSPHOPROTEIN P53,TUMOR SUPPRESS ... | ||
| -- | -- | SYNTHETIC CONSTRUCT | -- |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402