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GENERAL
TITLE
UBIQUITIN LIGATION TO F-BOX PROTEIN SUBSTRATES BY SCF-RBR E3-E3 SUPER- ASSEMBLY: CUL1-RBX1-SKP1-SKP2-CKSHS1-CYCLIN A-CDK2-P27
DATE LAST MODIFIED
10 Mar 2021
RELEASE
10 Feb 2021
OBSOLETE
CLASSIFICATION
LIGASE
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
3.8
RESOLUTION RANGE LOW
3.8
PUBMED ID
DOI
10.1038/S41586-021-03197-9
PDBe
--
LIGANDS
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| P0ABP8 | CUL1 | ESCHERICHIA COLI | HUMAN | CUL-1 | ||
| P61024 | CKS1B, CKS1, PNAS-143, PNAS-16 | ESCHERICHIA COLI | HUMAN | CKS-1 | Mutations | |
| P63000 | CDK2, CDKN2 | ESCHERICHIA COLI | HUMAN | CELL DIVISION PROTEIN KINASE 2,P33 PROTEIN KINASE | ||
| P0ABQ4 | CDKN1B, KIP1 | ESCHERICHIA COLI | HUMAN | CYCLIN-DEPENDENT KINASE INHIBITOR P27,P27KIP1 | ||
| P0ABP8 | SKP1, EMC19, OCP2, SKP1A, TCEB1L | ESCHERICHIA COLI | HUMAN | CYCLIN-A/CDK2-ASSOCIATED PROTEIN P19,P19A,ORGAN OF ... | ||
| P0ABQ4 | SKP2, FBXL1 | ESCHERICHIA COLI | HUMAN | CYCLIN-A/CDK2-ASSOCIATED PROTEIN P45,F-BOX PROTEIN ... | ||
| P0ABP8 | CCNA2, CCN1, CCNA | ESCHERICHIA COLI | HUMAN | CYCLIN-A,CYCLIN A |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402