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GENERAL
TITLE
CRYO-EM STRUCTURE OF THE COMPOUND 2 AND GLP-1-BOUND HUMAN GLP-1 RECEPTOR-GS COMPLEX
DATE LAST MODIFIED
-
RELEASE
14 Jul 2021
OBSOLETE
CLASSIFICATION
BIOSYNTHETIC PROTEIN
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
2.5
RESOLUTION RANGE LOW
2.5
PUBMED ID
DOI
10.1038/S41467-021-24058-Z
PDBe
--
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P63092 GNAS, GNAS1, GSP SPODOPTERA FRUGIPERDA HUMAN
ADENYLATE CYCLASE-STIMULATING G ALPHA PROTEIN
Mutations
P54311 GNB1 SPODOPTERA FRUGIPERDA RAT
TRANSDUCIN BETA CHAIN 1
Mutations
P63212 GNG2 SPODOPTERA FRUGIPERDA BOVINE
G GAMMA-I
Mutations
-- -- SYNTHETIC CONSTRUCT --
P01275 -- -- HUMAN -- Mutations
P43220 GLP1R SPODOPTERA FRUGIPERDA HUMAN
GLP-1R
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402