7F3Z

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 7F3Z_1

Chain 7F3Z_A

Chain 7F3Z_B

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GENERAL

TITLE

DOUBLE MUTANT PLASMODIUM FALCIPARUM DIHYDROFOLATE REDUCTASE- THYMIDYLATE SYNTHASE (PFDHFR-TS-K1, C59R+S108N) COMPLEXED WITH TRIMETHOPRIM (TOP), NADPH AND DUMP

DATE LAST MODIFIED

16 Mar 2022

RELEASE

22 Sept 2021

OBSOLETE

CLASSIFICATION

STRUCTURAL PROTEIN

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 21

RESOLUTION RANGE HIGH

2.6

RESOLUTION RANGE LOW

51.54

PUBMED ID

34614393

DOI

10.1016/J.STR.2021.09.004

PDBe

LIGANDS

628 , 931919 , 1233543 , 1169600

Chains

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P42260	DHFR-TS	ESCHERICHIA COLI	PLASMODIUM FALCIPARUM	--
	C6K2K4	DHFR-TS	ESCHERICHIA COLI	PLASMODIUM FALCIPARUM	--

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402