7JUT

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 7JUT_1

Chain 7JUT_B

Chain 7JUT_C

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GENERAL

TITLE

CRYSTAL STRUCTURE OF KSR2:MEK1 IN COMPLEX WITH ANP-PNP, AND ALLOSTERIC MEK INHIBITOR SELUMETINIB

DATE LAST MODIFIED

30 Dec 2020

RELEASE

30 Sept 2020

OBSOLETE

CLASSIFICATION

TRANSFERASE/TRANSFERASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 61 2 2

RESOLUTION RANGE HIGH

3.09

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1038/S41586-020-2760-4

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	Q5SJ80	KSR2	SPODOPTERA FRUGIPERDA	HUMAN	HKSR2
	Q96LB1	MAP2K1, MEK1, PRKMK1	SPODOPTERA FRUGIPERDA	RABBIT	MAPKK 1,ERK ACTIVATOR KINASE 1,MAPK/ERK KINASE 1,M ...

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402