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GENERAL
TITLE
EGFR KINASE (T790M/V948R) IN COMPLEX WITH OSIMERTINIB AND EAI045
DATE LAST MODIFIED
18 May 2022
RELEASE
8 Sept 2021
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.19
RESOLUTION RANGE LOW
49.91
PUBMED ID
-
DOI
10.1038/S41467-022-30258-Y
PDBe
7JXM
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| P00533 | EGFR, ERBB, ERBB1, HER1 | SPODOPTERA FRUGIPERDA | HUMAN | PROTO-ONCOGENE C-ERBB-1,RECEPTOR TYROSINE-PROTEIN ... | Mutations | |
| Q7Z5Q1 | EGFR, ERBB, ERBB1, HER1 | SPODOPTERA FRUGIPERDA | HUMAN | PROTO-ONCOGENE C-ERBB-1,RECEPTOR TYROSINE-PROTEIN ... | ||
| P00533 | EGFR, ERBB, ERBB1, HER1 | SPODOPTERA FRUGIPERDA | HUMAN | PROTO-ONCOGENE C-ERBB-1,RECEPTOR TYROSINE-PROTEIN ... | Mutations | |
| P00533 | EGFR, ERBB, ERBB1, HER1 | SPODOPTERA FRUGIPERDA | HUMAN | PROTO-ONCOGENE C-ERBB-1,RECEPTOR TYROSINE-PROTEIN ... | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402