7KYK

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 7KYK_A

Chain 7KYK_B

Chain 7KYK_C

Chain 7KYK_D

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GENERAL

TITLE

CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM DIHYDROOROTATE DEHYDROGENASE BOUND WITH INHIBITOR DSM589 (ETHYL 3-METHYL-4-((4- (TRIFLUOROMETHYL)BENZO[D]OXAZOL-7-YL)METHYL)-1H-PYRROLE-2- CARBOXYLATE)

DATE LAST MODIFIED

8 Dec 2021

RELEASE

19 May 2021

OBSOLETE

CLASSIFICATION

OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 21

RESOLUTION RANGE HIGH

2.15

RESOLUTION RANGE LOW

PUBMED ID

33876936

DOI

10.1021/ACS.JMEDCHEM.1C00173

PDBe

7KYK

LIGANDS

350048 , 3435 ,

Chains

Target Protein	Gene	Expression System	Organism	Synonims	Actions
Q08210	PFF0160C	ESCHERICHIA COLI	PLASMODIUM FALCIPARUM (ISOLATE 3D7)	DHODEHASE,DIHYDROOROTATE OXIDASE	Mutations
Q08210	PFF0160C	ESCHERICHIA COLI	PLASMODIUM FALCIPARUM (ISOLATE 3D7)	DHODEHASE,DIHYDROOROTATE OXIDASE	Mutations
Q08210	PFF0160C	ESCHERICHIA COLI	PLASMODIUM FALCIPARUM (ISOLATE 3D7)	DHODEHASE,DIHYDROOROTATE OXIDASE	Mutations
Q08210	PFF0160C	ESCHERICHIA COLI	PLASMODIUM FALCIPARUM (ISOLATE 3D7)	DHODEHASE,DIHYDROOROTATE OXIDASE	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402