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GENERAL
TITLE
CRYO-EM STRUCTURE OF THE HUMAN ADENOSINE A1 RECEPTOR-GI2-PROTEIN COMPLEX BOUND TO ITS ENDOGENOUS AGONIST
DATE LAST MODIFIED
13 Oct 2021
RELEASE
8 Sept 2021
OBSOLETE
CLASSIFICATION
SIGNALING PROTEIN
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
3.3
RESOLUTION RANGE LOW
3.3
PUBMED ID
DOI
10.1038/S41586-021-03897-2
PDBe
--
LIGANDS
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| P04899 | GNAI2, GNAI2B | TRICHOPLUSIA NI | HUMAN | ADENYLATE CYCLASE-INHIBITING G ALPHA PROTEIN | Mutations | |
| P62873 | GNB1 | TRICHOPLUSIA NI | HUMAN | TRANSDUCIN BETA CHAIN 1 | Mutations | |
| P59768 | GNG2 | TRICHOPLUSIA NI | HUMAN | G GAMMA-I | Mutations | |
| P30542 | CHRM4, ADORA1 | TRICHOPLUSIA NI | HUMAN | -- | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402