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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE HUMAN DYRK1A KINASE DOMAIN BOUND TO ABEMACICLIB
DATE LAST MODIFIED
1 Dec 2021
RELEASE
24 Nov 2021
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
1.82
RESOLUTION RANGE LOW
44.69
PUBMED ID
DOI
10.1038/S41467-021-26935-Z
PDBe
Chains
Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
---|---|---|---|---|---|---|
Q7Z3J3 | DYRK1A, DYRK, MNB, MNBH | ESCHERICHIA COLI 'BL21-GOLD(DE3)PLYSS AG' | HUMAN | DUAL SPECIFICITY YAK1-RELATED KINASE,HP86,PROTEIN ... | ||
Q13627 | DYRK1A, DYRK, MNB, MNBH | ESCHERICHIA COLI 'BL21-GOLD(DE3)PLYSS AG' | HUMAN | DUAL SPECIFICITY YAK1-RELATED KINASE,HP86,PROTEIN ... | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402