7O7K

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 7O7K_A

Chain 7O7K_B

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GENERAL

TITLE

CRYSTAL STRUCTURE OF THE HUMAN DYRK1A KINASE DOMAIN BOUND TO ABEMACICLIB

DATE LAST MODIFIED

1 Dec 2021

RELEASE

24 Nov 2021

OBSOLETE

CLASSIFICATION

TRANSFERASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 21

RESOLUTION RANGE HIGH

1.82

RESOLUTION RANGE LOW

44.69

PUBMED ID

DOI

10.1038/S41467-021-26935-Z

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P49792	DYRK1A, DYRK, MNB, MNBH	ESCHERICHIA COLI 'BL21-GOLD(DE3)PLYSS AG'	HUMAN	DUAL SPECIFICITY YAK1-RELATED KINASE,HP86,PROTEIN ...
	Q13627	DYRK1A, DYRK, MNB, MNBH	ESCHERICHIA COLI 'BL21-GOLD(DE3)PLYSS AG'	HUMAN	DUAL SPECIFICITY YAK1-RELATED KINASE,HP86,PROTEIN ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402