7PG6

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 7PG6_1

Chain 7PG6_A

Chain 7PG6_B

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GENERAL

TITLE

CRYSTAL STRUCTURE OF PI3KALPHA IN COMPLEX WITH THE INHIBITOR NVP- BYL719

DATE LAST MODIFIED

12 Oct 2022

RELEASE

24 Aug 2022

OBSOLETE

CLASSIFICATION

TRANSFERASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 21

RESOLUTION RANGE HIGH

2.499

RESOLUTION RANGE LOW

PUBMED ID

DOI

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P42336	PIK3CA	SPODOPTERA FRUGIPERDA	HUMAN	PI3-KINASE SUBUNIT ALPHA,PI3K-ALPHA,PI3KALPHA,PTDI ...	Mutations
	P27986	PIK3R1, GRB1	SPODOPTERA FRUGIPERDA	HUMAN	PI3-KINASE REGULATORY SUBUNIT ALPHA,PI3K REGULATOR ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402