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GENERAL
TITLE
CRYO-EM STRUCTURE OF HUMAN FULL-LENGTH EXTRASYNAPTIC ALPHA4BETA3DELTA GABA(A)R IN COMPLEX WITH THIP (GABOXADOL), HISTAMINE AND NANOBODY NB25
DATE LAST MODIFIED
20 Apr 2022
RELEASE
13 Apr 2022
OBSOLETE
CLASSIFICATION
MEMBRANE PROTEIN
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
2.9
RESOLUTION RANGE LOW
2.9
PUBMED ID
DOI
10.1038/S41586-022-04517-3
PDBe
--
LIGANDS
--
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| P61006 | GABRA4 | HOMO SAPIENS | HUMAN | GABA(A) RECEPTOR SUBUNIT ALPHA-4 | ||
| P28472 | GABRB3 | HOMO SAPIENS | HUMAN | GABA(A) RECEPTOR SUBUNIT BETA-3 | Mutations | |
| P61006 | GABRB3 | HOMO SAPIENS | HUMAN | GABA(A) RECEPTOR SUBUNIT BETA-3 | ||
| P28472 | GABRB3 | HOMO SAPIENS | HUMAN | GABA(A) RECEPTOR SUBUNIT BETA-3 | Mutations | |
| P61006 | GABRD | HOMO SAPIENS | HUMAN | GABA(A) RECEPTOR SUBUNIT DELTA | ||
| P61006 | -- | ESCHERICHIA COLI | LAMA GLAMA | -- | ||
| P61006 | -- | ESCHERICHIA COLI | LAMA GLAMA | -- |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402