FEATURES

FAMILY

DESCRIPTION

Also known as MHETH_IDESA, ISF6_0224. Involved in the degradation and assimilation of the plastic poly(ethylene terephthalate) (PET), which allows I.sakaiensis to use PET as its major energy and carbon source for growth. Likely acts synergistically with PETase to depolymerize PET. Catalyzes the hydrolysis of mono(2-hydroxyethyl) terephthalate (MHET) into its two environmentally benign monomers, terephthalate and ethylene glycol. Does not show activity against PET, bis(hydroxyethyl) terephthalate (BHET), pNP-aliphatic esters or typical aromatic ester compounds catalyzed by the tannase family enzymes, such as ethyl gallate and ethyl ferulate.

EXTERNAL LINKS

uniprot
enzyme classification

ISF6_0224

Mono(2-hydroxyethyl) terephthalate hydrolase

ISF6_0224

Molecular Synopsis