FEATURES

FAMILY

DESCRIPTION

Also known as BICL1_MOUSE, Bicdl1, Bicdr1, Ccdc64. Component of secretory vesicle machinery in developing neurons that acts as a regulator of neurite outgrowth. Regulates the secretory vesicle transport by controlling the accumulation of Rab6-containing secretory vesicles in the pericentrosomal region restricting anterograde secretory transport during the early phase of neuronal differentiation, thereby inhibiting neuritogenesis. Interacts with KIF1C. Interacts with RAB6A and RAB6B; interaction is specific to Rab6.

EXTERNAL LINKS

uniprot
enzyme classification

Bicdl1

Mutations

Mutation(s) distribution

Mutations table