FEATURES

FAMILY

DESCRIPTION

Also known as NB_ARTS2, Arth_3010. Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo. Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification

Arth_3010

Peroxynitrite isomerase

Arth_3010

Structural Ligandability

Domains Chains

Distribution