BMA10229_A3218 (Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase)
FEATURES
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ORGANISM
Burkholderia mallei (strain NCTC 10229)
FAMILY
DESCRIPTION
Also known as RRAAH_BURM9, BMA10229_A3218. Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity). Homotrimer.
Also known as RRAAH_BURM9, BMA10229_A3218. Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (
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BMA10229_A3218

Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase

Molecular Synopsis