FEATURES

FAMILY

DESCRIPTION

Also known as GATF_PICST, GTF1. Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Required for proper protein synthesis within the mitochondrion. Subunit of the heterotrimeric GatFAB amidotransferase (AdT) complex, composed of A, B and F subunits.

EXTERNAL LINKS

uniprot
enzyme classification

GTF1

Glutamyl-tRNA(Gln) amidotransferase subunit F, mitochondrial

GTF1

Structural Ligandability

Domains Chains

Distribution