FEATURES

FAMILY

DESCRIPTION

Also known as XMT1_COFCA, XMT1. Involved in the biosynthesis of caffeine (PubMed:17401201, PubMed:17434991). Specific for xanthosine (PubMed:17434991). Cannot use xanthosine 5'-monophosphate (XMP) as substrate (PubMed:17434991). Directly produces 7-methylxanthine, and therefore the methyl transfer and nucleoside cleavage may be coupled (PubMed:17434991). Catalyzes the 7-N-methylation of xanthosine, but does not have 1-N- or 3-N-methylation activity (PubMed:17434991). Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification

XMT1

Mutations

Mutation(s) distribution

Mutations table