FEATURES

FAMILY

DESCRIPTION

Also known as IRAD_ECO45, iraD. Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during oxidative stress. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway. Interacts with RssB.

EXTERNAL LINKS

uniprot
enzyme classification

iraD

Anti-adapter protein IraD

iraD

Molecular Synopsis