FEATURES

FAMILY

iron/ascorbate-dependent oxidoreductase family

DESCRIPTION

Also known as DIOX1_PAPSO, T6ODM, DIOX1. Non-heme dioxygenase catalyzing the conversion of thebaine to neopinone. Catalyzes also, with lower efficiency, the 6-O-demethylation of oripavine to morphinone. No activity with (S)-reticuline, salutaridine, papaverine, (S)-corytuberine, (S)-scoulerine, pavine, noscapine or codeine.

EXTERNAL LINKS

uniprot
enzyme classification

T6ODM

Thebaine 6-O-demethylase

T6ODM

Molecular Synopsis