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FEATURES

FAMILY

DESCRIPTION

Also known as WEE2_CHICK, WEE2, WEE1B. Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis. Required to maintain meiotic arrest in oocytes by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry (By similarity).

Also known as WEE2_CHICK, WEE2, WEE1B. Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis. Required to maintain meiotic arrest in oo ...

EXTERNAL LINKS

uniprot
enzyme classification

WEE2

Wee1-like protein kinase 2

Structural Ligandability

Domains Chains

Distribution

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