FEATURES

FAMILY

small leucine-rich proteoglycan (SLRP) family

DESCRIPTION

Also known as CHAD_HUMAN, CHAD, SLRR4A. Promotes attachment of chondrocytes, fibroblasts, and osteoblasts. This binding is mediated (at least for chondrocytes and fibroblasts) by the integrin alpha(2)beta(1). May play an important role in the regulation of chondrocyte growth and proliferation (By similarity). Mostly monomeric (By similarity). Interacts with collagen type II.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CHAD

Chondroadherin

CHAD

Molecular Synopsis