FEATURES

FAMILY

DESCRIPTION

Also known as CYPX_BACSU, cypX, cyp134, cypB. Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. Catalyzes the oxidation of cyclo(L-Leu-L-Leu) (cLL) to yield pulcherriminic acid which forms pulcherrimin via a nonenzymic reaction with Fe(3+). Substrates with small alkyl groups (cAA, cLG, cLP) exhibit weaker binding to CYP134A1, but substrates with larger hydrophobic side chains bind in a similar regime to cLL. Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification

cypX

Pulcherriminic acid synthase

cypX

Molecular Synopsis