FEATURES

DESCRIPTION

Also known as CYH3_HUMAN, CYTH3, ARNO3, GRP1, PSCD3. Promotes guanine-nucleotide exchange on ARF1 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. Plays a role in the epithelial polarization (By similarity). Interacts with TAMALIN (By similarity). Interacts with ARF6 (PubMed:23940353). Interacts with FRMD4A (By similarity). Interacts with FRMD4B (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CYTH3

Mutations

Mutation(s) distribution

Mutations table