FEATURES

FAMILY

DESCRIPTION

Also known as STX6_HUMAN, STX6. Involved in intracellular vesicle trafficking. Identified in a complex containing STX6, STX12, VAMP4 and VTI1A (PubMed:17159904). Binds EEA1 (By similarity). Interacts with VPS45A (By similarity). Interacts with MARCHF2 and MARCHF3 (By similarity). Interacts with GOPC (PubMed:11384996). Interacts with UHRF1BP1L (via C-terminal coiled-coil domain) (PubMed:20163565). Interacts with BAIAP3; this interaction is increased in the presence of calcium (PubMed:28626000).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

STX6

Mutations

Mutation(s) distribution

Mutations table