FEATURES

FAMILY

PYR/PYL/RCAR abscisic acid intracellular receptor family

DESCRIPTION

Also known as PYR1_ARATH, PYR1, ABIP6, RCAR11. Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition. Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) when activated by ABA (PubMed:19407142, PubMed:19624469, PubMed:19769575, PubMed:23844015, PubMed:21658606). Can be activated by both (-)-ABA and (+)-ABA (PubMed:23844015). Promotes drought tolerance (PubMed:29970817). Homodimer (PubMed:21658606, PubMed:19898494, PubMed:19933100). Binds ABA on one subunit only. Interacts with HAB1, AHG3, ABI1 and ABI2 when complexed to ABA, and possibly with other PP2Cs (PubMed:19407142, PubMed:19874541, PubMed:19898420, PubMed:19898494, PubMed:19933100). Binds to CARs protein in an ABA-independent manner, both at the plasma membrane and in the nucleus (PubMed:26719420). Interacts directly with CAR1 and CAR4 (PubMed:25465408, PubMed:26719420). Interacts with CARK1 in the cytosol (PubMed:29928509, PubMed:19407142, PubMed:19874541, PubMed:19898420, PubMed:19898494, PubMed:19933100, PubMed:21658606, PubMed:25465408, PubMed:26719420). Interacts with AIP1 in an abscisic acid-dependent manner (PubMed:29928509). Interacts with FREE1 (via N-terminus) (PubMed:27495812). Interacts with the E3 ubiquitin-protein ligase RSL1 at the plasma membrane (PubMed:25330042).

EXTERNAL LINKS

PYR1

Mutations

Mutation(s) distribution

Mutations table