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FAMILY

PurK/PurT family

DESCRIPTION

Also known as PURT_PYRHO, purT. Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. Homodimer.

Also known as PURT_PYRHO, purT. Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide ...

EXTERNAL LINKS

uniprot
enzyme classification

purT

Formate-dependent phosphoribosylglycinamide formyltransferase

Mutations

Mutation(s) distribution

Mutations table

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