FEATURES

FAMILY

DESCRIPTION

Also known as PR40A_HUMAN, PRPF40A, FBP11, FLAF1, FNBP3, HIP10, HYPA. Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. May play a role in cytokinesis. May be involved in pre-mRNA splicing. Interacts with the N-terminus of HTT. Interacts with the phosphorylated C-terminal domain of POLR2A. Interacts with AKAP8L, SF1, SRPK1, ENAH, ATBF1 and MECP2 (By similarity). Interacts through the WW domains with formin proline-rich regions and with WASL/N-WASP (By similarity).

Also known as PR40A_HUMAN, PRPF40A, FBP11, FLAF1, FNBP3, HIP10, HYPA. Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic ...

EXTERNAL LINKS

PRPF40A

Pre-mRNA-processing factor 40 homolog A

PRPF40A

Molecular Synopsis