FEATURES

FAMILY

DESCRIPTION

Also known as SRP72_HUMAN, SRP72. Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. Binds the 7S RNA only in presence of SRP68. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function. Signal recognition particle consists of a 7S RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SRP72

Signal recognition particle subunit SRP72

Mutations

Mutation(s) distribution

Mutations table

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