FEATURES

FAMILY

DESCRIPTION

Also known as CRP_HUMAN, CRP, PTX1. Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. Homopentamer. Pentraxin (or pentaxin) have a discoid arrangement of 5 non-covalently bound subunits. Interacts with FCN1; may regulate monocyte activation by FCN1.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CRP

C-reactive protein

CRP

Molecular Synopsis