FEATURES

FAMILY

DESCRIPTION

Also known as VTDB_HUMAN, GC. Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation. Associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes. Interacts with LRP2; the interaction is required for renal uptake of GC in complex with 25-hydroxyvitamin D3 (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

GC

Mutations

Mutation(s) distribution

Mutations table